Clinical Outcomes and Inflammatory Markers Should Be Kept in Mind when Assessing the Mean Platelet Volume in Patients with Infective Endocarditis

tion of inflammatory markers with antimicrobial therapy is a good predictor of favorable late outcome [3, 4] . In addition, one of the determinants of an adverse outcome in IE is the presence of systemic embolization, particularly cerebral embolization. IE vegetations consist of bacteria, platelets and inflammatory cells in a fibrin mesh. Thus, the results of the current study should be combined and endorsed with clinical outcomes like systemic embolization and correlation with other proinflammatory markers like C-reactive protein [3, 4] and neutrophil-to-lymphocyte ratio [5] . Medications like aspirin which can affect the MPV values should be reported along with the other medications administered to patients.